In the 22nd August 2021 edition, our weekly monitor reached 359 new calls (!) recently opened by European Institutions and Agencies. This week we gave a specific look to Horizon Europe-funded calls in Cluster 4: Digital Industry and Space and in particular to calls included in the Destination 6: A human-centred and ethical development of digital and industrial technologies. The European Commission provided a specific infosession on the Destination 6 calls the last 6th of July. The AI4 Copernicus Consortium launched a new call for proposals for citizen-driven social challenges based on AI (Artificial Intelligence) technologies and Earth Observation (EO) Data.